Group D-2 化学構造 (Chemical Structure)  

● Dibenz(a,h) acridine (ジベンツ(a, h) アクリジン)
   CAS: 226-36-8  Laboratory  MW: 279.35
CA CHL/IU Max ( 1.0 mg/mg, ±S9),  3-21h
1)
CT Rat /Embryo Min ( 0.1μg/ml)
2)
1) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, LIC, Tokyo (1998)  (Tables in English)
2) Freeman AE, et al,: J. Natl. Cancer Inst., 51, 799 (1973)

●Dibenz(a,j) acridine (ジベンツ(a, j) アクリジン)  
  224-42-0  Laboratory   279.35
AM Sal. Min ( 5μg/plate, +S9)
1)
CA CHL/IU Max ( 1.0 mg/mg, +S9),  3-21h
2)
CT Rat/embryo Min ( 0.1μg/ml)
3)
1) McCann J., et al. : Proc. Natl Acad. Sci. (USA), 72, 5135-5139 (1975)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro. LIC, Tokyo (1998)
  (Tables in English)
3) Freeman AE, et al,: J. Natl. Cancer Inst., 51, 799 (1973)

● Dibenz(c,h) acridine (ジベンツ(c,h) アクリジン)
  224-53-3 Laboratory   279.35
CA CHL/IU Min( 0.19 mg/ml,+S9), 3-21h D20= 0.14; TR= 310
1
CT BHK21c113 Max ( ?,  +S9) (soft agar assay),
2
1) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test in vitro LIC, Tokyo (1998)   (Tables in English)
2) Styles JA: Brit. J. Cancer, 37, 931-936 (1978)

●Dibenzofuran  (Diphenylene oxide) (ジベンゾフラン)
  
132-64-9 Industry   168.19
AM Sal Max (?)
1)
CA CHL/IU Max ( 0.1 mg/ml, +MS9), 6-18h
2)
1) (?)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, LIC, Tokyo (1998)   (Tables in English)

p,p'-Dibenzoylguinone dioxime (p,p'-ベンゾイルキノンジオキシム
 
   120-52-5  Industry   346.34
AM Sal./E.coli Min ( 50 μg/plate, +S9)
1)
CA CHL/IU Min ( 4.0 mg/ml, -S9), 24h
2)
1) Ministry of Labour, Japan: Mutagenicity Test Data of Exist. Chem. Sub.,JETOC (Ed.), pp. 110 (1996)  (Tables in English)
2) Ministry of Labour, Japan: Mutagenicity Test Data of Exist. Chem. Sub.,JETOC (Ed.), pp .540 (1996)  (Tables in English)

Dibenzoyl peroxide (過酸化ベンゾイル)
     94-36-0  Industry   242.23

AM Sal./ E.coli Max ( 313 μg/plate, ±S9)
1)
1) Ministry of Labour, Japan: Mutagenicity Test Data of Exist. Chem. Sub., JETOC (Ed.) Suppl. 2, pp. 176 (1997) (Tables in English)

● Dibenzoylthiamine
(ジベンゾイルチアミン)
    299-88-7
   Food  490.59 
AM Sal. Max (?)
1)
CA CHL/IU Max ( 0.03 mg/ml, -S9), 24-48h  (No data for +S9)
2)
1) (?)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, LIC, Tokyo (1998)   (Tables in English)

● Dibenzoylthiamine-HCl (ジベンゾイルチアミン・塩酸)   
    35660-60-7
 Food   581.09
AM Sal. Max (5.0 mg/ml, ±S9)
1)
CA CHL/IU Max (0.05 mg/ml, -S9), 24-48h (No data for +S9)
2)
1) Ishidate MJr (Ed): Data Book for Mutagenicity in Bacteria, LIC.Tokyo (1991) (Tables in English)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration TestIn Vitro, LIC, Tokyo (1998)   (Tables in English)

1,4-Dibromobenzene (1,4-ジブロモベンゼン) #
   106-37-6 Industry  
235.92
AM Sal. Max (0.8 mg/ml, ±S9)
1)
CA CHL/IU Min (2.2 mg/ml, +S9), 6-18h
1)
1) Ministry of Health & Welfare, Japan: Tox. Test. Rep. Environ. Chem., Vol. 2, pp. 353 (1995) (Tables in English)

1,4-Dibromobutane 1,4-ジブロモブタン)
  110-52-1 Industry   215.92
AM Sal./E.coli Min ( 78.1 μg/plate, -S9): spa= 1640
1)
1) Ministry of Labour, Japan: Mutagenicity Test Data of Exist. Chem. Sub., Vol. 1, JETOC (1996)  (Tables in English)

● Dibromochloromethane (ジブロモクロロメタン)
   
124-48-1 Industry  208.29
AM Sal. Max (?)
1)
CA CHL/IU Min ( 0.098 mg/ml, +S9), 3-21h:  D20= 0.09; TR= 140
2)
MNv Mice Max ( 200 mg/kg x 4, ip),  24h
3)
1) Natl. Inst. Hygien. Sci., Tokyo, (?)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, , LIC, Tokyo (1998)   (Tables in English)
3) Hayashi M., et al., :Fd. Chem. Toxic. ,26, 487-500 (1988)

● 1-(1, 2-Dibromoehtyl)-3,4-dibromocyclothexane
  
 
3322-93-8 Industry  427.83
CA CHL/IU Min (0.125 mg/ml,+S9), 6-18h D20= 0.16; TR= 30
1)
1) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test in vitro, LIC, Tokyo (1998)   (Tables in English)

 
1,5-Dibromopentane +
    111-24-0  Industry   229.94
AM Sal/ E.coli Min( 78.1 μg/plate, -S9), spa= 230
1)
1) Ministry of Labour, Japan: Mutagenicity Test Data of Exist. Chem. Sub., Vol. 1, pp. 373, JETOC (1996)  (Tables in English)

1,2-Dibromopropane (Propyrene dibromide) 1,2-ジブロモプロパン)
      78-75-1 Industry   201.89
AM Sal/ E.coli Min( 78.1 μg/plate, -S9), spa= 230
1)
1) Ministry of Labour, Japan: Mutagenicity Test Data of Exist. Chem. Sub., Suppl. 2, pp. 37, JETOC (2000)  (Tables in English)

1,3-Dibromopropane 1,3-ジブロモプロパン)+
      109-64-8 Industry   201.89
AM Sal./E.coli Min( 19.5μg/plate, +S9); spa= 1130 (TA1535)
1)
CA CHL/IU Min ( 0.3 mg/ml, -S9), 48h: D20= 0.3; TR= 88
1)
1) Ministry of Labour, Japan: Mutagenicity Test Data of Exist. Chem. Sub.,JETOC (1996)  (Tables in English)

● 2,3-Dibromo-1-propanol
(2,3-ジブロモ-1-プロパノール)
    
96-13-9 Industry  217.89
AM Sal. Min (?) 
1)
CA CHL/IU Min ( 0.3 mg/ml, -S9), 48h: D20= 0.3; TR= 88
2)
1) (?)
2) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, LIC, Tokyo (1998)   (Tables in English)

● 2,3-Dibromopropyl dihydrogen phosphate
   
5324-12-9     Industry  297.87
CA CHL/IU Max (2.0 mg/ml, -S9, 24-48h), (No data for +S9)
1)
1) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, , LIC, Tokyo (1998)   (Tables in English)

2,3-Dibromosuccinic acid (2,3-ジブロモコハク酸 #
      526-78-3  
Industry  275.88
AM Sal./E.coli Max ( 5.0 mg/ml, ±S9)
1)
CA CHL/IU Max ( 1.4 mg/ml, ±S9, 6-18h )
1)
1) Ministry of Health & Welfare, Japan: Tox. Test. Rep. Environ. Chem., Vol. 2, pp. 401 (1995) (Tables in English)

Top Page (トップページ)
Abbreviation  (省略記号) 
Mutagenicity (変異原性)
Test Systems (試験法の種類)
Technical Problems (技術的問題点)
List of Compounds(化合物リスト)
Evaluation of Results (試験結果の評価)