Group F-1 ‰»Šw\‘’@(Chemical Structure)  

œ Famotidine
@@@
CASF 76824-35-6@ @Laboratory @@MW: 337.43@@
CA CHL/IU Max( 4.0 mg/ml, -S9), 24, 48h@(No data for +S9)
 
1)
1) Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, LIC, Tokyo (1998) (Tables in English)

œ Fenamiphos (ENT 27572)
@@@22224-92-6 Pesticede @ 303.4
AM Sal Max(?)
 
1, 2)
AM E. coli Max(?)
 
2)
DLv Mice Max(?)
 
1, 3)
MN Mice Max(?)
 
1)
1) Kimmerle G: Communication to TLV Committee (1982)
2) Hanna, PJ & Dyer KF: Mutation Res. 28, 405-420 (1975)
3) Food and agriculture Organization/WHO (1974); WHO Pesticide Residues Series No.4, WHO, Geneva (1975)

US-NTP Genotoxicity Screening:
@Ames Test: 

œ Fenitrothion @iƒtƒFƒjƒgƒƒ`ƒIƒ“G@ƒXƒ~ƒ`ƒIƒ“j
@@@
122-14-5@Pesticide@ 277.23
REC B.subtilis Max ( 26 mg/disk)   1)
AM Sal/E.coli Max (?)   1)
AM Sal Max (?)   2)
AM E.coli (spot) Max (?)   3)
YM Yeast Max (?)   4)
SM Drosophilla Min ( 5 mM, 72hr) ›w 5)
SLRL Drosophilla Max ( 150 ppm, fd)   6)
PLN Vicia faba Min (?) › 7)
SCE Hum. Ly Min (?)
 
8)
CA CHL/IU Min ( 0.05 mg/ml, +S9), 3-21h@D20=0.067; TR=200
›
9)
SM V79 Max (0.3 mMA}S9)   10)
MNv Mice ICR Max ( 800 mg/kg)
 
1)
CAv Rats Max (?)   11)
1) Suzuki H & Miyamoto J: J. Pesticide Sci., , 1, 253-259 (1976)
2) Shirasu Y, Environ Qual Saf. 4, 226-231 (1975)
3) Nagy Z., et al., Acta Microbiol. Acad. Sci. Hung. 22(3), 309-314 (1975)
4) Yadav AS., et al., Mutation Res., 105 6), 403-407 (1982)
5) Tripathy NK &Patnaik KK, Mutation Res., 260,@225-231 (1991)
6) Velazquez A, et al., Mutagenesis, 2 (5), 333-336 (1987)
7) Njagi GE & Gopalan HB, Cytologia, 46, 169-172 (1981)
8) Yu Y., et al.: Chinese J. Prevent Med., 20,-354-355 (1986)
9)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test In Vitro, LIC, Tokyo (1998) (Tables in English)
10) Hara M., et al., Mutation Res., 222, 53-61 (1989)
11) Malhi PK & Grover IS, Mutation Res., 188, 45-51 (1987)

œ Fenoxaprop-ethyl
@@
66441-23-4@Pesticide@ 361.8
AM Sal Max ( 5.0 mg/plate, }S9)
 
1)
CA Human LY Max ( 1.0 mg/ml, -S9)@D20=0.18; TR=110: (No data for +S9)
 
1)
MNv Mice Max ( 1.8 g/kg )
 
1)
UDS @? Max (?)
 
1)
1) Hoechist Japan Co., Lid.: J. Pesticide Sci., 17, S17-S23 (1992)

œ Fenoxycarb @iƒCƒ“ƒZƒK[j
@
@@72490-01-8@@Pesticide @ @ 301.34
REC B. subtilis Max ( 10 mg/disk)
 
1)
AM Sal Max ( 5 mg/plate)
 
1)
CA Human LY Max ( 10 ƒΚg/ml)
 
1)
1) Nihon Ciiba Geigy:, Co., Ltd., : J. Pesticide Sci., 16, 709-712 (1991)

œ Fenpyroximate @iƒ_ƒjƒgƒƒ“j
@@
134098 61-6@Pesticide @ @ 421.5
REC B. subtilis Max ( 0.5 mg/disk)
 
1)
AM Sal Max ( 5 mg/plate)
 
1)
CA Human LY Max ( 20 ƒΚg/ml)
 
1)
MNv Mice Max ( 2.0 g/kg x 1)
 
1)
SM V79 Max(?)
 
1)
UDS ? Max(?)
 
1)
1) Nihon Ciba Geigy:, Co., Ltd., : J. Pesticide Sci., 16, 709-712 (1991)

œ Fenugreek resinex
@@
68990-15-8@Food/Natural@ @
AM Sal Min (?)
›
1)
CA CHL/IU Max ( 8.0 mg/ml, -S9), 24, 48h (No data for +S9)
 
2)
1) Natl. Inst. Hygien. Sci., Tokyo?
2)
Sofuni T. (Ed.): Data Book of Chromosomal Aberration Test in vitro LIC, Tokyo (1998) (Tables in English)

œ Fensulfothion
@@
115-90-2 @Pesticide @ 308.35
DL Mice Max (?)
 
1)
1) Loeser E & Kimmerie G: Nachr, 24 (3), 407-430 (1971)

œ Fenthion @(Baytex; Entex)
@@@
55-38-9@Pesticide @ 278.34
AM Sal/E. coli Max(?)@
 
1,2)
AM S. cerevisiae Max(?)
 
3)
UDS Human Fb Max(?)
 
3)
DLv Mice Max(?)@
 
4)
MN Mice Max(?)@
 
4)
1) Sirasu Y, et al,: Mutation Res., 40, 19-30 (1976)
2) Hanna PJ &Dyer KF: Mutation Res., 28, 405-420 (1975)
3) Simmon VF, et al,: EPA-600/1-77-028, NTIS Pub., Natl. Tech. Inform. Service, Springfield, VA (1977)
4) Imai H: Acta. Soc. Ophehaimol, Japan 79(8), 1067-1076 (1975)

US-NTP Genotoxicity Screening:
›@Ames Test:
’
›@CA Test with CHO cells:
 
›@SCE Test with CHO cells:
›

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