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(Methodology of Mutagenicity@(Genotoxicity) Tests)
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PDABBONDANDOLO, A.  (1977) Prospects for evaluating genetic damage in mammalian cells in culture.  Mutat. Res., 42: 279-298.ABRAHAMSON, S. & LEWIS, E.B.  (1971) The detection of mutations in  Drosophila melanogaster.  In: Hollaender, A., ed. Chemical mutagens: principles and methods for their detection, New York, London, Plenum Press, pp. 461-487.

QDADAIR, G.M., CARVER, J.H., & WANDRES, D.L.  (1980)  Mutagenicity testing in mammalian cells. I. Derivation of a Chinesehamster ovary cell line heterozygous for the adenine phosphoribosyl transferase and thymidine kinase loci.  Mutat. Res.,72: 187-205.

RDADLER, I.-D.  (1970)  Cytogenic analysis of Ascites tumour cells in mice in mutation research. In: Vogel, F. & Rohrborn, G., ed.  Chemical mutagenesis in mammals and man, Berlin, Heidelberg, New York, Springer-Verlag, pp. 251-259.

SDADLER, I.-D.  (1974)  Comparative cytogenetic study after treatment of mouse spermatogonia with mitomycin C.  Mutat. Res.,23: 369-379.

TDADLER, I.-D.  (1981)  Transplacental cytogenetic effects by TEM, mitomycin C, and benzo(a)pyrene. Mutat. Res.,85: 299-300.

UDADLER, I.-D.  (1982)  Male germ cell cytogenetics. In: Hsu, T.C., ed.  Cytogenetic assays of environmental mutagens, New York, Allanheld Osmun & Co., pp. 249-276.

VDADLER, I.-D.  (1985)  Cytogenetic tests in mammals. In: Venitt, S. & Parry, J.M., ed.  Mutagenicity testing: a  practical approach, Oxford, IRL Press, pp. 275-306.

WDADLER, I.-D. & BREWEN, J.G.  (1982)  Effects of chemicals on chromosome aberration production in male and female germcells. In: Hollaender, A. & de Serres, F.J., ed.  Chemical mutagens: principles and methods for their detection, New York,London, Plenum Press, Vol. 7, pp. 1-35.

XDAHMED, M. & GRANT, W.F.  (1972)  Cytological effect of the pesticides Phosdrin and Bladex on  Tradescantia and  Vicia  faba. Can. J. Genet. Cytol., 14: 157-165.

PODALBANESE, R., TOPHAM, J.C., EVANS, E., CLARE, M.G., & TEASE, C.  (1984)  Mammalian germ cell cytogenetics. In: Dean, B.J., ed.  UKEMS Sub-Committee on Guidelines for Mutagenicity  Testing. Part II. Supplementary Tests, Swansea, United Kingdom Environmental Mutagen Society.

PPDAMACHER, D.E. &PAILLET, S.C.  (1983)  The activation of procarcinogens to mutagens by cultured rat hepatocytes in the L5178Y/TK mutation assay.  Mutat. Res., 113: 77-88.

PQDAMACHER, D.E. & TURNER, G.N.  (1981)  Promutagen activation by rodent-liver post-mitochondrial fractions in the L5178Y/TK cell mutation assay.  Mutat. Res., 74: 485-501.

PRDAMACHER, D.E. & TURNER, G.N.  (1982a)  Mutagenic evaluation of carcinogens and non-carcinogens in the L5178Y/TK assay utilizing post-mitochondrial fractions (S9) from normal rat liver.  Mutat. Res., 97: 49-65.

PSDAMACHER, D.E. & TURNER, G.N.  (1982b)  The effect of liver post-mitochondrial fraction concentration from Arochlor 1254-treated rats on promutagen activation in L5178Y cells. Mutat. Res., 97: 131-137.

PTDAMES, B.N., DURSTEN, W.E., YAMASAKI, E., & LEE, F.W.  (1973)  Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.  Proc. Natl Acad. Sci. (USA), 70: 2281-2285.

PUDAMES, B.N., MCCANN, J., & YAMASAKI, E.  (1975)  Methods for detecting carcinogens and mutagens with the  Salmonella/mammalian microsome mutagenicity test.  Mutat. Res., 31: 347-364.

PVDANDERSON, D., BATEMAN, A., & MCGREGOR, D.  (1983)  Dominant lethal mutation assays. In:  Report of the UKEMS Sub-Committee on Guidelines for Mutagenicity Testing, Swansea, United Kingdom Environmental Mutagen Society, pp. 143-164.

PXDNDRAE, U. & GREIM, H.  (1979)  Induction of DNA repair replication by hydroxyurea in human lymphoblastoid cellsmediated by liver micromes and NADPH.  Biochem. biophys. Res. Commun., 87: 50-58.

QODASHBY, J., DE SERRES, F.J., DRAPER, M., ISHIDATE, M. Jr, MARGOLIN, B.H, MATTER, B.E., & SHELBY, M.D., ed.  (1985)  Evaluation of short-term tests for carcinogens. Report of the International Programme on Chemical Safety's Collaborative Study on In vitro Assays, Amsterdam, Oxford, New York, Elsevier Science Publishers (Progress in Mutation Research, Vol. 5)

QPDAUERBACH, C  (1962a)   Mutation. An introduction to research on mutagenesis. Part 1. Methods, Edinburgh, London, Oliver and Boyd, 176 pp.

QQDAUERBACH, C.  (1962b)  The production of visible mutations in  Drosophila by chloroethyl methylsulfonate (CB 1506).  Genet. Res., 3: 461-466.

QRDBAKER, R.M.  (1979)  Nature and use of ouabain-resistant mutants. In: Hsie, A.W., O'Neill, J.P., & McElheny, V.K., ed. Mammalian cell mutagenesis: the maturation of the test  systems, New York, Cold Spring Harbor Laboratory, pp. 237-24 (Banbury Report No. 2).

QSDBAKER, R.M., BRUNETTE, D.M., MANKOVITZ, R., THOMPSON, L.H., WHITMORE, G.F., SIMINOVITCH, L., & TILL, J.E.  (1974)  Ouabain-resistant mutants of mouse and Chinese hamster cells. Cell, 1: 9-21.

QTDBARTSCH, H., CAMUS, A.-M., & MALAVEILLE, C.  (1976)  Comparative mutagenicity of  N-nitrosamines in a semi-solid and liquid incubation system in the presence of rat or human tissue fractions.  Mutat. Res., 37: 149-162.

QUDBARTSCH, H., MALAVEILLE, C., CAMUS, A.-M., MARTEL-PLANCHE, G., BRUN, G., HAUTEFEUILLE, A., SABADIE, N., BARBIN, A.,KUROKI, T., DREVON, C., PICOLLI, C., & MONTESANO, R.  (1979)  Validation and comparative studies on 180 chemicals with  S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems.  Mutat. Res., 76: 1-50.

QVDBARTSCH, H., MALAVEILLE, C., CAMUS, A.-M., MARTEL-PLANCHE, G., BRUN, G., HAUTEFEUILLE, A., SABADIE, N., BARBIN, A.,KUROKI, T., DREVPM, C., PICCOLI, S., & MONTESANO, R.  (1980)  Bacterial and mammalian mutagenicity tests: validation and comparative studies on 180 chemicals. In: Montesano, R., Bartsch, H., & Tomatis, L., ed.  Molecular and cellular  aspects  of carcinogen screening tests, Lyons, International Agency for Research on Cancer, pp. 179-241 (IARC  Scientific PublicationsNo. 27).

QWDBARTSCH, H., KUROKI, T., ROBERFROID, M., & MALAVEILLE, C.  (1982)  Metabolic activation systems  in vitro for carcinogen-mutagen screening tests. In: de Serres, F.J. & Hollaender, A., ed.  Chemical mutagens, New York, London, Plenum Press, Vol. 7, pp. 95-161.

QXDBATEMAN, A.J.  (1958)  Mutagenic sensitivity of maturing germ cells in the male mouse.  Heredity, 12: 213-232.

RODBATEMAN, A.J.  (1966)  Testing chemicals for mutagenicity in a mammal.  Nature (Lond.), 210: 205-206.

RPDBATEMAN, A.J. & EPSTEIN, S.S.  (1971)  Dominant lethal mutations in mammals. In: Hollaender, A., ed. Chemical  mutagens: principles and methods for their detection, New York, London, Plenum Press, Vol. 2, pp. 541-568.

RQDBECKER, H.J.  (1966)  Genetic and variegation mosaics in the eye of  Drosophila. Curr. Topics dev. Biol., 1: 155-171.

RRDBENDER, M.A., GRIGGS, H.G., & BEDFORD, J.S.  (1974)  Mechanisms of chromosomal aberration production. III. Chemicals  and ionizing radiation.  Mutat. Res., 23: 197-212.

RSDBOLLER, K. & SCHMID, W.  (1970)  [Chemical mutagenesis in mammals. The bone marrow of the Chinese hamster as an  in vivo test system.]  Haematologische Befunde nach Behandlung mit Trenimon. Humangenetik, 11: 35-54 (in German).

RTDBOYCE, R.P. & HOWARD-FLANDERS, P.  (1964)  Release of ultraviolet light-induced thymine dimers and DNA in  E. coli K-12.  Proc. Natl Acad. Sci. (USA), 51: 293-300.

RUDBOYUM, A.  (1968)  Isolation of mononuclear cells and granulocytes from human blood.  Scand. J. clin. Lab. Invest.,21(Suppl. 97): 77-89.

RVDBRADLEY, M.O., BHUYAN, B., FRANCIS, M.C., LANGENBACH, R., PETERSON, A., & HUMBERMAN, E.  (1981)  Mutagenesis by chemical agents in V79 Chinese hamster cells:   a review and analysis of the literature: a Report of the Gene-tox program.  Mutat. Res., 87: 81-142.

RWDEBRENNEKE, H.  (1937)  [Radiation damage to mouse and rat sperm, observed from the early development of the ova.] Strahlentherapie, 60: 214-238 (in German).

RXDBREWEN, J.G. & PRESTON, R.J.  (1982)  Cytogenic analysis of mammalian oocytes in mutagenicity studies. In: Hsu, T.C., ed. Cytogenic assays of environmental mutagens, New York, Allanheld Osmun & Co., pp. 277-287.

SODBREWEN, J.G. & STETKA, D.G.  (1982)  Cytogenetic events in vivo. In: Heddle, J.A., ed.  Mutagenicity: new horizons in genetic toxicology, New York, London, Academic Press, pp. 351-384.

SPDBREWEN, J.G., PAYNE, H.S., JONES, K.P., & PRESTON, R.J.  (1975)  Studies on chemically-induced dominant lethality.  I. The cytogenetic basis of MMS-induced dominant lethality in post-meiotic male germ cells.  Mutat. Res., 33: 239-250.

SQDBRIDGES, B.A., CLEMMESEN, J., & SUGIMURA, T.  (1979)  Cigarette smoking - does it carry a genetic risk?  Mutat. Res. 65, 71-81 (ICPEMC Publication No. 3)

SRDBRUCE, W.R. & HEDDLE, J.A.  (1979)  The mutagenic activity of 61 agents as determined by the micronucleus,  Salmonella  and sperm abnormality assays.  Can. J. Genet. Cytol., 21: 319-335.

SSDBRUSICK, D.  (1980)  Genetic risk estimation. In:  Principles  of genetic toxicology, New York, London, Plenum Press, pp. 109-135.

STDBUCKTON, K.E., JACOBS, P.A., COURT BROWN, W.M., & DOLL, R.  (1962)  A study of the chromsome damage persisting after X-ray therapy for ankylosing spondolitis.  Lancet, 2: 676-682.

SUDBURTON, K.  (1956)  A study of the conditions and the mechanism of the diphenylamine reaction for the colorimetric  estimation of DNA.  Biochem. J., 62: 315-323.

SVDCALLEN, D.F. & PHILPOT, R.M.  (1977)  Cytochrome P-450 and the activation of promutagens in  Saccharomyces cerevisiae. Mutat. Res., 45: 309-324.

SWDCASKEY, C.T. & KRUSH, G.D.  (1979)  The HPRT locus.  Cell, 16: 1-9.

SXDCLAYSON, D.B.  (1981)  Carcinogens and carcinogen enhancers. Mutat. Res., 86: 217-229 (ICPEMC Working Paper No 2/3).

TODCLEAVER, J.E.  (1982)  DNA damage, DNA repair, and DNA replication in short-term tests for exposure to mutagens. In:Kora, K.C., Douglas, G.R., & Nestmann, E.R., ed.  Mutagenesis, human population monitoring, and genetic risk assessment, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 111-124 (Progress in Mutation Research, Vol. 3).

TPDCLEAVER, J.E. & THOMAS, G.H.  (1981)  Measurement of unscheduled synthesis by autoradiography. In: Friedberg, E.C. & Hanawalt, P.C., ed.  DNA repair: a laboratory manual of  research procedures, New York, Basel, Marcel Dekker, pp. 277-287.

TQDCLIVE, D., FLAMM, W.G., MACHESKI, M.R., & BERNHEIM,N.J.  (1972)  A mutational assay system using the thymidine kinase locus in mouse lymphoma cells.  Mutat. Res., 16: 77-87.

TRDCLIVE, D., JOHNSON, K.O., SPECTOR, J.F.S., BATSON, A.G., & BROWN, M.M.M.  (1979)  Validation and characterization of  the L5178Y TK+/- mouse lymphoma mutagen assay system:  Mutat. Res. 59: 61-108.

TSDCLIVE, D., MCCUEN, R., SPECTOR, J.F.S., PIPER, C., & MAVOURIM, K.H.  (1983)  Report of the Gene-Tox program on L5178Y. Mutat. Res., 115: 225-251.

TTDCOLE, J., ARLETT, C.F., LOWE, J., & BRIDGES, B.A.  (1982)  The mutagenic potency of 1,8-dinitropyrene in cultured mouse lymphoma cells.  Mutat. Res., 93: 213-220.

TUDCOLE, R.J., TAYLOR, N.A., COLE, J., & ARLETT, C.F.  (1979)  Transplacental effects of chemical mutagens detected by the micronucleus test.  Nature (Lond.), 277: 317-318.

TVDCOLE, R.J., TAYLOR, N.A., COLE, J., & ARLETT, C.F.  (1981)  Short-term tests for transplacentally active carcinogens.  I. Micronucleus formation in fetal and maternal mouse  erythroblasts.  Mutat. Res., 80: 141-157.

TWDCOLLINS, A.R.S., SHOR, S.L., & JOHNSON, R.T.  (1977)  The inhibition of repair in UV-irradiated human cells.  Mutat. Res., 42: 413-432.

TXDCOMBES, R.D., ANDERSON, D., BROOKS, T.M., NEALE, S., & VENITT, S.  (1984)  The detection of mutagens in urine, faeces, and body fluids. In: Dean, B.J., ed.  UKEMS Subcommittee on  Guidelines for Mutagenicity Testing. Part II. Supplementary Tests, Swansea, United Kingdom Environmental Mutagen Society.

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UPDCONSTANTIN, M.J. & NILAN, R.A.  (1982)  Chromosome aberrations in barley  (Hordeum vulgare): a report of the US Environmental Portection Agency Gene-Tox Program.  Mutat. Res., 99: 13-36.

UQDCONSTANTIN, M.J. & OWENS, E.T.  (1982)  Introduction and perspectives of plant genetic and cytogenetic assays: a report of the US Environmental Protection Agency Gene-Tox Program. Mutat. Res., 99: 1-12.

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USDDAVIES, P.J., TIPPINS, R.S., & PARRY, J.M.  (1978)  Cell-cycle variation in the induction of lethality and mitotic recombination after treatment with UV and nitrous acid in the yeast  Saccharomyces cerevisiae. Mutat. Res., 51: 327-328.

UTDDEAN, B.J.  (1969)  Chemically-induced chromosome damage. Lab. Anim., 3: 157-174.

UUDDEAN, B.J.  (1985)  Summary report on the performance of cytogenetic assays in cultured mammalian cells. In:  Ashby, J.,  de Serres, F.J., Draper, M., Ishidate, M., Jr, Margolin, B., Matter, B., & Shelby, M.D., ed.  Evaluation of short-term  tests for carcinogens, Amsterdam, Oxford, New York, Elsevier Science Publishers, pp. 69-83 (Progress in Mutation Research,Vol. 5).

UVDDEAN, B.J. & DANFORD, N.D.  (1985)  Assays for the detection of chemically-induced chromosome damage in cultured mammalian cells. In: Venitt, S. & Parry, J.M., ed.  Mutagenicity testing: a practical approach, Oxford, IRL Press, pp. 187-232.

UWDDEAN, B.J. & HODSON-WALKER, G.  (1979)  An  in vitro chromosome assay using cultured rat-liver cells.  Mutat. Res., 64: 329-337.

UXDDEAN, B.J., ANDERSON, D., & SRAM, R.J.  (1981)  Mutagenicity of selected chemicals in the mammalian dominant lethal assay. In: de Serres, F.J. & Shelby, M.D., ed.  Comparative chemical mutagenisis, New York, London, Plenum Press, pp. 487-538.

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VUDDRAPER, M.H. & GRIFFIN, J.P.  (1980)  Draft guidelines on mutagenicity testing of new drugs issued by the CPMP. A four test screen.  Arch. Toxicol., 46: 9-19.

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VWDEHLING, U.H., CUMMING, R.B., & MALLING, H.V.  (1968)  Induction of dominant lethal mutations by alkylating agents in male mice.  Mutat. Res., 5: 417-428.

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WQDEPSTEIN, S.S. & SHAFNER, H.  (1968)  Chemical mutagens in the human environment.  Nature (Lond.), 219: 385-387.

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WTDEVANS, H.J. & O'RIORDAN, M.L.  (1975)  Human peripheral blood lymphocytes for the analysis of chromosomal aberrations in mutagen tests.  Mutat. Res., 31: 135-148.

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WVDFAHRIG, R.  (1975)  Development of host-mediated mutagenicity tests: yeast systems. Recovery of yeast cells out of  testes, liver, lung, and peritoneum of rats.  Mutat. Res., 31: 381-394.

WWDFAHRIG, R.  (1977)  The mammalian spot test with mice.  Arch. Toxikol., 38: 87-98.

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XQDFISCHER, G.A., LEE, S.Y., & CALABRESI, P.  (1974)  Detectionof chemical mutagens using a host-mediated assay (L5178Y)  mutagenesis system.  Mutat. Res., 26: 501-511.

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XTDGARNER, R.C., MILLER, E.C., MILLER, J.A., GARNER J.V., & HANSON, R.S.  (1971)  Formation of a factor lethal for S. typhimurium TA 1530 and TA 1531 on incubation of aflatoxin B1 with rat liver microsomes.  Biochem. biophys. Res. Commun., 45: 774.

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XVDGENOROSO, W.M., CAIN, K.T., KRISHNA, M., & HUFF, S.W.  (1979)  Genetic lesions induced by chemicals in spermatozoa and spermatids of mice are repaired in the egg.  Proc. Natl. Acad. Sci. (USA), 76: 435-437.

XWDGOCKE, E., ECKHARDT, K., KING, M.-T., & WILD, D.  (1982)  Some statistical aspects of spontaneous lethal mutations in Drosophila. Mutat. Res., 104: 239-242.

XXDGRAF, U., JUON, H., KATZ, A.J., FREI, J.J., & WURGLER, G.E.  (1983)  A pilot study on a new Drosophila spot test.  Mutat. Res. Lett., 120: 233-239.

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POPDGRANT, W.F.  (1982)  Chromosome aberration assays in Allum: a report of the US Environmental Protection Agency Gene-Tox Program.  Mutat. Res., 99: 273-291.

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PORDGUPTA, R.A. & SINGH, B.  (1982)  Mutagenic responses of five independent genetic loci in CHO cells to a variety of mutagens: development and characteristics of a mutagen screening system based on selection for multiple drug-resistan markers.  Mutat. Res., 94: 449-466.

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POTDHASEMAN, J.K. & SOARES, E.R.  (1976)  The distribution of fetal death in control mice and its implications on statistical tests for dominant lethal effects.  Mutat. Res., 41: 277-288.

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PPODHOLSTEIN, N., MCCANN, J., ANGELOSANTO, F.A., & NICHOLS, W.W.  (1979)  Short-term tests for carcinogens and mutagens. Mutat. Res., 64: 133-226.

PPPDHOZIER, J., SAWYER, J., MOORE, M., HOWARD, B., & CLIVE, D.  (1981)  Cytogenic analysis of the L5187Y TK+1- TK1 mouse  lymphoma mutagenesis assay system.  Mutat. Res., 84: 167-181.

PPQDHSIE, A.W., O'NEILL, J.P., & MCELHENY, V.K., ed.  (1979)  Mammalian cell mutagenesis: the maturation of test systems, New York, Cold Spring Harbor Laboratory (Banbury Report No. 2).

PPRDHSIE, A.W., CASCIANO, D.A., CROUCH, D.B., KRAHN, D.F., O'NEILL, J.P., & WHITFIELD, B.L.  (1981)  The use of Chinesehamster ovary cells to quantity specific locus mutation and to determine mutagenicity of chemicals, A report of the  Gene-tox program.  Mutat. Res., 86: 193-214.

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yCited from Environ. Health Criteria 51: Guide to Short-Term Tests for
Detecting Mutagenic and Carcinogenic Chemicals (IPCS/WHO, 1985)
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@̑̎Ql@iReviews)@
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